For Patients

About Low Dose Immunotherapy (LDI)

LDI is an innovative approach for treating allergies and autoimmune issues, focusing on gently teaching the immune system to react correctly. Unlike traditional treatments, LDI is safer and treats a wider range of conditions without severe reactions. We use sublingual application, avoiding the potential discomfort associated with injection-based treatment. It involves much lower doses and is more patient-friendly. The treatment frequency is less than conventional methods, adapting as patients improve. LDI offers hope even for those who haven’t found success with other therapies, aiming for long-term relief.

Revolutionary Immune Training

LDI retrains the immune system, enhancing tolerance and response.

Broad Condition Spectrum

Effective for various allergies, autoimmune diseases, and chronic conditions.


Foods, animals, pollens, mold, dust, chemicals and other triggers.

Expert-led Approach

Guided by Dr. Ty Vincent’s pioneering expertise in LDI treatment methods.

What to expect

When embarking on the LDI treatment journey, you can expect a thoughtful, patient-centered process. Initially, we start with lower doses, closely observing your body’s reaction. Your feedback is key in adjusting these doses for optimal effect. Through careful monitoring and gradual adjustments, the goal is to achieve lasting relief from symptoms.

Starting Treatment

We begin with a gentle approach, choosing a low concentration of LDI to minimize any possible aggravation of symptoms.

Observing Responses

You’ll monitor how your body reacts to the treatment. If there’s no change, the dose might be too weak. If symptoms worsen temporarily, it could be too strong.

Adjusting Doses

Depending on your response, we’ll carefully adjust the dosage, seeking the optimal level for improvement without discomfort.

Ongoing Evaluation

As treatment progresses, we continually reassess and tweak dosages, aiming for long-term symptom relief.

Active Participation

Your input is crucial. By sharing detailed feedback, we can more effectively tailor the treatment to your needs.

Book Now

Ready to take the first step towards personalized healthcare? Book your appointment for Low Dose Immunotherapy today. Choose a time that suits you through our convenient online scheduling system. Your initial consultation is $650, or if you need a quicker appointment, contact us to join the waitlist for a rush consultation at $1050. Only one appointment is required for treatment, but follow-up appointments are available upon request.

Upon booking, you’ll receive our comprehensive patient handbook to help prepare you for your journey with us. Begin your path to better health now!

What does the initial consultation include?

Your initial consultation is a 1-hour appointment with Dr. Ty Vincent, where together you will review your health history. Based on extensive experience and an understanding of your health status and sensitivity level, Dr. Vincent will recommend a starting dose type and potency. This is the only appointment required for treatment, though follow-up appointments are offered at $650 by request.

What other costs are involved?

Treatment Review & Dose Fee

Following your initial consultation, you’ll receive 1-5 syringes of your assigned antigen(s) by mail.

1-5 syringes: $175 per person for each dose cycle. We will send up to 2 core doses per shipment.

$35 for each additional syringe past 5, each dose cycle.

The frequency of dosing is entirely personal. After reaching your core dose, you are likely to dose once every 7 weeks until achieving lasting tolerance.

Also included in this fee is ongoing email support from both Dr. Vincent and Jinette, including treatment review by Dr. Vincent which encompasses the time to review your dose-response, give feedback on next steps, and prepare doses.

Shipping costs are additional and dependent on patient location.

For services or sales taking place in the State of Hawaii, please note all fees are subject to the State of Hawaii Excise Tax.

Is there one standardized plan?


Each individual receives a customized treatment plan according to their health status and sensitivity level. 

The number of syringes, frequency of dosing, and types of antigens are determined through collaboration by Dr. Vincent and the patient. 

Do not pay your invoice until it reflects your desired dose plan. The invoice reflects what will be shipped and in what manner. Should you notice any discrepancies on your invoice, please email Jinette and include your mailing address for quick look-up. 


How does LDI work?

Allergy and autoimmunity represent a loss of appropriate immune “tolerance.” The idea behind this form of immunotherapy is to “retrain” immune tolerance in the immune system, either individually or in very large collections at once. This seems like a very basic concept, but it is truly profound.  Dr. Ty Vincent developed this technique in 2009, beginning with autologous samples and a collection of yeast. In 2009, he developed LDI for Lyme disease with a large degree of success.  Since that time, he has developed over seventy antigens to treat an extensive list of allergies, chronic auto-immune conditions, and illnesses thought to be chronic infections.  Low Dose Immunotherapy (LDI) is also profoundly different from conventional immunotherapy used for environmental allergies.

Do I need to get injections?

No! Dr. Vincent’s LDI therapy is entirely sublingual, suitable for all ages and temperaments. 

Is LDI safe? What are the risks?

LDI is far safer, more effective, and more user-friendly than conventional immunotherapy. It is also able to treat many more conditions than conventional allergy therapy. The doses are so much lower.  There has never been a reported case of anaphylaxis from an LDI dose and you cannot even theoretically “react” directly to an allergen dose. In contrast, life-threatening reactions are known to occur with the high doses of antigen given during conventional allergy shots. Adverse responses to LDI can arise if the dilution is too strong/potent, but that can be avoided by starting in a more cautious dilution range when a patient has more severe reactions or disease. LDI flares cause an aggravation of the existing symptoms, it is temporary, lasting a length of time proportional to how far off the dose was from their optimal dilution. 

How often do you take LDI doses?

LDI doses are given far less frequently than conventional immunotherapy. Effective doses may be needed as frequently as every four to six weeks, and then it usually spaces out from there as patients do better with each dose.  Initially, doses are given every week or so as “titration doses” as we look for a significant response. Some patients will be able to stop therapy at some point and can remain disease-free for long periods of time, but their immune problems can return at any time following some catalytic immune stressor or event. We have treated many patients for allergies who had failed conventional immunotherapy or other techniques, so failure with other therapies is not predictive of whether LDI will work for you.

What is the Low Dose Immunotherapy (LDI) treatment process?

In the beginning, we start with a conservative approach, using a weaker dilution to minimize the risk of symptom exacerbation. Drawing from his experience and your unique story, Dr. Vincent estimates the starting point, and you confirm your comfort level.

For each dose attempted, there are several possible outcomes:

  1. Too Weak of a Dose: No change in symptoms. We can proceed with a more potent dilution about one week later (the lower the number, the more potent the dose), with the timeline adjusted based on specific conditions, needs, and additional therapies.
  2.   Too Strong of a Dose: Exacerbation of existing symptoms (LDI will not cause new symptoms), known as an LDI flare, may start within the first 48 hours. The duration of the flare is proportional to the deviation from the optimal dilution. If a flare occurs, we wait 7 weeks for the immune system to reset, then restart from a weaker dilution.
  3.   Nearly Right Dose: Partial improvement or complete relief for a limited duration. In this case, we adjust by giving a slightly larger dose in terms of dilution or volume.

4. Core Dose: If symptoms or reactions disappear entirely for 6 weeks or longer, this is the “CORE DOSE.” Initially taken every 6-7 weeks, patients may choose to wait for symptoms to return and then take another core dose as needed. Doses can be spaced further over time, even up to a year or more apart!

How long do I have to take LDI doses?

It’s essential to recognize that immune-related problems fluctuate, and while LDI may offer relief for years, symptoms can resurface due to various factors. Effective LDI core doses may require periodic adjustments, which is why we should not use the term “cure.”  The immune system is complex and tolerance may need to be restored periodically. Patients can expect to take effective doses every 7 weeks for budgeting purposes. We typically provide two core doses at a time, covering at least 14 weeks or much longer once the ideal dose is determined. If longer intervals are maintained between doses, the overall cost of treatment decreases over time.

How much does LDI cost?

Plan on ordering doses about every 7 weeks, until a core dose is met, then plan on the dose fee about every 14 weeks or longer for budgeting purposes.

Join Our Support Group

Connect with fellow Low Dose Immunotherapy (LDI) patients in our dedicated Facebook support group. Share your experiences, ask questions, and find support from a community that understands your journey. Our group is a safe space to gain insights, offer encouragement, and stay informed about the latest LDI news and resources.

Join us today and be part of a supportive network that’s here for you every step of the way!

Start your journey

Connect with us to schedule a consultation. Trust in the care and expertise of Dr. Ty Vincent M.D., backed by proven results and professional accreditation. Your journey to wellness begins here.